Course Objectives
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\n\nThe objective of this course is to provide an intense update on advances in cancer biology, from carcinogenesis to epidemiology, etiology and therapy. The course aims to provide a translational view of cancer, from basic science to clinical applications.
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The course program will update participants on:
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\n\nGenetic and epigenetic alterations; tumour dynamics and hallmarks of cancer;
\n\tIntroduction to metakaryotic stem cells; biology and physiology of cancer cells;
\n\tEpidemiology and etiology of cancer;
\n\tCarcinogenic mechanisms and development of cancer;
\n\tTherapy of cancer: from conventional therapies to novel approaches.
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Duration of the course
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\n\nThe course comprises 20 lectures. Attendance is possible following registration and payment of a fee.
\n\nHowever, the course includes one conference open to the entire scientific community (free of charge) on the discovery of metakaryotic stem cells.
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Lectures: 60 mins followed by 30 mins discussion; 4 lectures/day
\n\nTotal duration of lectures: 30 hours
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Teaching language: English only
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Audience
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\n\nThe course is aimed mainly at international post-graduate students (master and PhD students), young researchers, post-doctoral researchers, oncologists and University lecturers. However, the course is open to the entire international scientific community at University level. Previous knowledge on oncobiology is highly recommended.
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Certificates of participation
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\n\nCertificates of participationwill be issued based on confirmation of participation in at least 80% of the lectures (corresponding to at least 16 lectures of the 20 available). Confirmation of participation will be based on signature on an attendance sheet, whichwill be available during each lecture.
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","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-ipf53n0f":{"type":"StyledText","id":"dataItem-ipf53n0f","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"WELCOME TO OPORTO
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-ipfc9gn8":{"type":"SvgShape","id":"dataItem-ipfc9gn8","metaData":{"isPreset":true,"schemaVersion":"1.0","isHidden":false},"link":"#dataItem-ipffavhe"},"dataItem-ipffavhe":{"type":"AnchorLink","id":"dataItem-ipffavhe","metaData":{"isPreset":true,"schemaVersion":"1.0","isHidden":false},"anchorName":"About","pageId":"#k42v9","anchorDataId":"#dataItem-ihkkejy61"},"dataItem-j8zzu03k":{"type":"StyledText","id":"dataItem-j8zzu03k","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Professor of Genetics, Toxicology and Biological Engineering at the MIT in USA
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":["#textLink_j9iasffz"]},"dataItem-j906azd6":{"type":"StyledText","id":"dataItem-j906azd6","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"\n\n
09,00h – Welcome reception
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\n\n09,30h - “Introduction: a synthesis of epidemiology, stem cell physiology, genetics, epigenetics and toxicology”
\n\nProf. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at theMassachusetts Institute of
\n\nTechnology (MIT) in USA
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11,00h - Coffee break
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11,30h - “Tumour dynamics, heterogeneity and the hallmarks of cancer”
\n\nProf. Manuel Sobrinho-Simões, Jubilee Professor of Pathology of the Medical Faculty and Director of the Institute of
\n\nMolecular Pathology and Immunology of the University of Porto (PATIMUP)
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13,00h - Lunch break
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14,00h – “Genetic alterations in sporadic and hereditary cancers”
\n\nProf. Manuel Teixeira, Director of Department of Genetics and Research Center at IPO-Porto and Guest Full Professor at
\n\nICBAS-UP
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15,30h - Coffee break
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16,00h – “Epigenetic alterations in cancers”
\n\nProf. Carmen Jerónimo, Leader of the Cancer Biology and Epigenetics Group at the Portuguese Oncology Institute of
\n\nPorto (IPO Porto) and Invited Associate Professor in Pathology and Molecular Genetics at ICBAS-UP
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17,30h - End session
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DAY 2 (January 9, TUESDAY)
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09,30h – “Molecular biology /Altered pathways in cancer cells”
\n\nProf. Natércia Teixeira, Full Professor at FFUP, Sub-Director of FFUP and leader of the Drug Target and Biomarkers
\n\nResearch Group at UCIBIO-REQUMTE
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\n\n11,00h – Coffee break
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\n\n11,30h – “Identification of biomarkers of cancer and therapeutic targets”
\n\nProf. Cecília Rodrigues, Full Professor at Faculty of Pharmacy, University of Lisbon (FFUL) and Director at iMed.ULisboa
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\n\n13,00h - Lunch break
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14,00h - “Physiological alterations in cancer and clinical implications”
\n\nProf. Jorge Gonçalves, Full Professor of Pharmacology at FFUP and Researcher at the Center for Drug Discovery and
\n\nInnovative Medicines (MedInUP)
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15,30h - Coffee break
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16,00h – “Introduction to metakaryotic biology, morphology and physiology of stem cells of fetal/juvenile development and cancers”
\n\nProf. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
\n\nTechnology (MIT) in USA
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17,30h - End session
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DAY 3 (January 10, WEDNESDAY)
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09,30h – “History of mortality from cancers in the United States, 1900-2010”
\n\nProf. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
\n\nTechnology (MIT) in USA
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\n\n11,00h – Coffee break
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\n\n11,30h – “Epidemiologic knowledge: impact on cancer policies and public health programs”
\n\nProf. Henrique Barros, Full Professor of Epidemiology at the Faculty of Medicine of the University of Porto (FMUP),
\n\nPresident of the Institute of Public Health from the University of Porto and President of the International Epidemiological
\n\nAssociation
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\n\n13,00h - Lunch break
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14,00h – “Etiopathogenesis of cancer: gene environment interactions”
\n\nProf. Fátima Carneiro, MD, PhD, Full Professor of Pathology (Medical Faculty of Porto), Head of Department of Anatomic
\n\nPathology (Centro Hospitalar São João) and Senior Researcher at IPATIMUP/i3S
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15,30h - Coffee break
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16,00h - “Integrating knowledge on epidemiology, biology, pathology and therapy of cancer – clinical cases”
\n\nProf. Rui Henrique, Director of Department of Pathology at IPO Porto and Invited Full Professor at ICBAS-UP
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\n\n17,30h - CONFERENCE OPEN TO ALL SCIENTIFIC COMMUNITY:
\n\n“Discovery of metakaryotic stem cells of human organs, tumours and atherosclerotic plaques”
\n\nDoctor Elena V. Gostjeva, Research Scientist at the Department of Biological Engineering, Massachusetts Institute of
\n\nTechnology (MIT) in USA
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19,30h - COURSE DINNER
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22,00h - End session
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DAY 4 (January 11, THURSDAY)
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09,30h – “The relevance of the environment in carcinogenesis”
\n\nProf. Raquel Soares, Full Professor at FMUP and Leader of Metabolism, nutrition & endocrinology Group at i3S
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\n\n11,00h – Coffee break
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11,30h – "Amended “two-stage” cancer model: required initiation and promotion events occur in mutator/hypermutable
\n\nnormal metakaryotic stem cells and promotion events occur in initiated metakaryotic preneoplastic stem cells”
\n\nProf. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
\n\nTechnology (MIT) in USA
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13,00h - Lunch break
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14,00h – “Molecular mechanisms of carcinogenesis”
\n\nProf. Fernando Remião, Associate Professor at FFUP and Senior Researcher at UCIBIO/REQUIMTE
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\n\n15,30h - Coffee break
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16,00h - “Biomarkers of genotoxicity/DNA damage”
\n\nProf. Nuno Oliveira, Assistant Professor with Aggregation, Faculty of Pharmacy, University of Lisbon (FFULisboa) -
\n\nDepartment of Toxicological and Bromatological Sciences and Researcher at iMed.ULisboa
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17,30h - End session
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DAY 5 (January 12, FRIDAY)
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09,30h - “From conventional to personalized therapy”
\n\nProf. Ana Bela Sarmento, Associate Professor with Agregation at FMUC; Group Leader at CIMAGO; Investigator at
\n\nCNC.IBILI and Clinical Hematologist at CHUC
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\n\n11,00h - Coffee break
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11,30h - “Cancer Drug Resistance”
\n\nProf. M. Helena Vasconcelos, Assistant Professor at FFUP and Leader of the Cancer Drug Resistance Group at
\n\nIPATIMUP/i3S
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13,00h - Lunch break
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14,00h - “Clinical trials: from the bench to the clinic”
\n\nProf. Lúcio Lara Santos, Professor of Surgical Oncology at ICBAS-UP, Head of Experimental Pathology and Therapeutics Group and
\n\nmember of Surgical Oncology Department of IPO-Porto
\n\n&
\n\nDr. Júlio Oliveira, Medical Oncologist and Clinical Pharmacologistat IPO Porto and PhD student in Medical Sciences at ICBAS-UP
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\n\n15,30h - Coffee break
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16,00h - “Metakaryotic cancer stem cells are constitutively resistant to X-rays and present-day chemotherapies but sensitive
\n\nto many common drugs: proposal for treating cancers by killing all neoplastic metakaryotic stem cells”
\n\nProf. William Thilly, Professor of Genetics, Toxicology and Biological Engineering at the Massachusetts Institute of
\n\nTechnology (MIT) in USA
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17,30h - Closing ceremony
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\n\n17,45h - Port wine tasting
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j90azh2t":{"type":"StyledText","id":"dataItem-j90azh2t","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Full Professor of Pharmacology and Researcher at the Center for Drug Discovery and Innovative Medicines (MedInUP) at FFUP
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":["#textLink_j9iav1tg"]},"dataItem-j9736t5q":{"type":"StyledText","id":"dataItem-j9736t5q","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Director of Department of Pathology at IPO Porto and Invited Full Professor at ICBAS-UP
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":["#textLink_j9iawa2k"]},"dataItem-j9746ox6":{"type":"StyledText","id":"dataItem-j9746ox6","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Associated Professor at FFUP and Senior Researcher at UCIBIO/REQUIMTE
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":["#textLink_j9iaxj4x"]},"dataItem-j974snon":{"type":"StyledText","id":"dataItem-j974snon","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Assistant Professor at FFUP and Leader of the Cancer Drug Resistance Group at IPATIMUP/i3S
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":["#textLink_j9iayvck"]},"dataItem-j975gq0b":{"type":"StyledText","id":"dataItem-j975gq0b","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Medical Oncologist and Clinical Pharmacologist at IPO Porto and
\n\nPhD student in Medical Sciences at ICBAS-UP
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":["#textLink_j9iazpfm"]},"dataItem-j976pomn":{"type":"AnchorLink","id":"dataItem-j976pomn","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"anchorName":"Programme","pageId":"#k42v9","anchorDataId":"#dataItem-j90auyso"},"dataItem-j9789jto":{"type":"BasicMenuItem","id":"dataItem-j9789jto","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"label":"Registration","isVisible":true,"isVisibleMobile":true,"items":[],"link":"#dataItem-j9789ju4"},"dataItem-j9789ju4":{"type":"AnchorLink","id":"dataItem-j9789ju4","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"anchorName":"Registration","pageId":"#k42v9","anchorDataId":"#dataItem-j978a8tm"},"dataItem-j978a8tm":{"type":"Anchor","id":"dataItem-j978a8tm","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"name":"Registration","compId":"comp-j978a8qw"},"dataItem-j978hkb5":{"type":"StyledText","id":"dataItem-j978hkb5","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Early Registration: until 30th November 2017
\n\nLate Registration: after 1st December 2017
\n\nRegistration Deadline: 17th December 2017
\n\nCourse date: 8th January to 12th January 2018
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","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j978r61o":{"type":"StyledText","id":"dataItem-j978r61o","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Early Registration
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\n\nStudents from University of Porto (UP): 50 Euros*
\n\nOthers: 80 Euros*
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\n\nLate Registration
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\n\nStudents from UP: 100 Euros*
\n\nOthers: 160 Euros*
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\n\n*Additional optional costs will be necessary if the participant wishes to include coffee-breaks, lunches and/or course dinner.
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\n\nThe registration fee includes the admission to the full-program of the International Intensive Course on Cancer Biology and the course material. Coffee-breaks, lunch and dinner are not included in the basic course fee.
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\n\nAdditional Optional Costs (ONLY available until 17th December 2017)
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\n\n10x Coffee Breaks: 36 Euros
\n\t5x Buffet Lunches: 66 Euros OR alternatively FFUP has a canteen. For more information please see FFUP canteen prices.
\n\tMeeting Dinner: 35 Euros
\n\tCertificates of participation will be issued based on confirmation of participation in at least 80% of the lectures (corresponding to at least 16 lectures of the 20 available). Confirmation of participation will be based on signature on an attendance sheet, which will be available during each lecture.
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j97a0m8z":{"type":"BasicMenuItem","id":"dataItem-j97a0m8z","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"label":"Location & Venue","isVisible":true,"isVisibleMobile":true,"items":["#dataItem-j98kz660","#dataItem-j98l7fhq"],"link":"#dataItem-j97a0mbn"},"dataItem-j97a0mbn":{"type":"AnchorLink","id":"dataItem-j97a0mbn","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"anchorName":"Location & Venue","pageId":"#k42v9","anchorDataId":"#dataItem-j97aqmw6"},"dataItem-j97aqmw6":{"type":"Anchor","id":"dataItem-j97aqmw6","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"name":"Location & Venue","compId":"comp-j97aqmst"},"dataItem-j97b56og":{"type":"StyledText","id":"dataItem-j97b56og","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"The International Intensive Course on Cancer Biology will be held at the Faculty of Pharmacy of the University of Porto (FFUP).
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\n\nAddress: Rua de Jorge Viterbo Ferreira, 228, 4050-313 - Porto, Portugal
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\n\nGPS coordinates: 41°08'51.3"N 8°37'26.1"W
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\n\nLectures: Salão Nobre of ICBAS/FFUP complex
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j97bger9":{"type":"LinkableButton","id":"dataItem-j97bger9","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"label":"ENJOY OPORTO","link":"#dataItem-j98l9bo8"},"dataItem-j97bhs2z":{"type":"StyledText","id":"dataItem-j97bhs2z","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Faculty of Pharmacy Porto University (FFUP)
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\n\nRua de Jorge Viterbo Ferreira, 228
\n\n4050-313 - Porto
\n\nPORTUGAL
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\n\nTelephone: +351 220 428 500
\n\nFax: +351 226 093 390
\n\nWeb: http://www.ff.up.pt
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For further information please contact:
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\n\nProfessor Helena Vasconcelos: helena.vasconcelos@ff.up.pt
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":["#link-j98l1ju2"]},"dataItem-j98l1ju9":{"type":"StyledText","id":"dataItem-j98l1ju9","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Organizing Committee
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\n\nPerson responsible for the course: Prof. M. Helena Vasconcelos, FFUP /IPATIMUP/i3S
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j9e64fwm":{"type":"Image","id":"dataItem-j9e64fwm","metaData":{"isPreset":false,"schemaVersion":"2.0","isHidden":false},"title":"","uri":"d63d11_62ad6d4bb96e45bdafd28326698ad9ff~mv2.jpg","description":"","width":884,"height":884,"alt":"","link":"#dataItem-j9e64fwn"},"dataItem-j9e64fwn":{"type":"PageLink","id":"dataItem-j9e64fwn","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"pageId":"#lmx8f"},"dataItem-j9e64fxj":{"type":"StyledText","id":"dataItem-j9e64fxj","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"M. Helena Vasconcelos, Ph.D.
\n\nAssistant Professor at FFUP and Leader of the Cancer Drug Resistance Group at IPATIMUP/i3S
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j9e66y10":{"type":"Image","id":"dataItem-j9e66y10","metaData":{"isPreset":false,"schemaVersion":"2.0","isHidden":false},"title":"","uri":"d63d11_775e8530b61e42f788365afc6a0cc42b~mv2.jpg","description":"","width":612,"height":612,"alt":"","link":"#dataItem-j9e66y101"},"dataItem-j9e66y101":{"type":"PageLink","id":"dataItem-j9e66y101","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"pageId":"#lmx8f"},"dataItem-j9e66y18":{"type":"StyledText","id":"dataItem-j9e66y18","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Cristina Xavier, Ph.D.
\n\nPost-Doc of Cancer Drug Resistance Group at IPATIMUP/i3S
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j9e671yk":{"type":"Image","id":"dataItem-j9e671yk","metaData":{"isPreset":false,"schemaVersion":"2.0","isHidden":false},"title":"","uri":"d63d11_ad81bad0f1fb4988be1dfc76cf078525~mv2_d_1287_1287_s_2.png","description":"","width":1287,"height":1287,"alt":"","link":"#dataItem-j9e671yl"},"dataItem-j9e671yl":{"type":"PageLink","id":"dataItem-j9e671yl","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"pageId":"#lmx8f"},"dataItem-j9e671yq":{"type":"StyledText","id":"dataItem-j9e671yq","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Hugo R. Caires, Ph.D.
\n\nPost-Doc of Cancer Drug Resistance Group at IPATIMUP/i3S
","stylesMapId":"CK_EDITOR_PARAGRAPH_STYLES","linkList":[]},"dataItem-j9e6755y":{"type":"Image","id":"dataItem-j9e6755y","metaData":{"isPreset":false,"schemaVersion":"2.0","isHidden":false},"title":"","uri":"d63d11_ded74d5614c84c0d9d93a96aaab312ba~mv2.png","description":"","width":853,"height":853,"alt":"","link":"#dataItem-j9e6755y1"},"dataItem-j9e6755y1":{"type":"PageLink","id":"dataItem-j9e6755y1","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"pageId":"#lmx8f"},"dataItem-j9e67563":{"type":"StyledText","id":"dataItem-j9e67563","metaData":{"isPreset":false,"schemaVersion":"1.0","isHidden":false},"text":"Marilene Estanqueiro, Ph.D. student
\n\nInvited Assistant at FFUP
\n\nand Ph.D. student of the Cancer Drug Resistance Group at IPATIMUP/i3S
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